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The use of these medications can further impede cognitive function for people with dementia, who are also more sensitive to side effects of medications.Sedatives can sometimes leave the patient with long-term or short-term amnesia.In both types of dependences, finding and using the sedative becomes the focus in life.

The paradoxical reactions may consist of depression, with or without suicidal tendencies, phobias, aggressiveness, violent behavior and symptoms sometimes misdiagnosed as psychosis.

In the event of an overdose or if combined with another sedative, many of these drugs can cause unconsciousness (see hypnotic) and even death.

There is some overlap between the terms "sedative" and "hypnotic".

Many sedatives can be misused, but barbiturates and benzodiazepines are responsible for most of the problems with sedative use due to their widespread recreational or non-medical use.

People who have difficulty dealing with stress, anxiety or sleeplessness may overuse or become dependent on sedatives.

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Sedatives and alcohol are sometimes combined recreationally or carelessly.

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